Intracellular Hyperthermia Using Magnetic Nanoparticles: A Novel Method for Hyperthermia Clinical Applications
نویسنده
چکیده
Magnetic nanoparticle-mediated intracellular hyperthermia has been a largely experimental modality of hyperthermia, but this treatment modality has the potential to achieve tumor targeted heating without any side effects. The technique consists of targeting magnetic nanoparticles to tumor tissue and then applying an external alternating magnetic field to induce heat generation by the magnetic nanoparticles. Among available magnetic nanoparticles, magnetite has been extensively studied. Recent years have seen remarkable advances in magnetite nanoparticle-mediated hyperthermia; both functional magnetite nanoparticles and alternating magnetic field generators have been developed. Currently, some clinical trials have been started, suggesting that time may have come for clinical applications in many hospitals. This paper describes recent advances in magnetite nanoparticle-mediated hyperthermia.
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